Description

2-Fluoro-4-Iodopyridin-3-Ol is a high-value halogenated pyridine derivative, serving as a critical building block in modern synthetic chemistry. Its unique structure, featuring both fluorine and iodine substituents, makes it an indispensable intermediate for constructing complex molecules with tailored properties. This compound is primarily sought after by research institutions and pharmaceutical companies engaged in the development of new active pharmaceutical ingredients (APIs), agrochemicals, and advanced materials.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Research: Used in the development of next-generation herbicides, fungicides, and pesticides, leveraging its halogenated pyridine core.
• Ligand & Catalyst Preparation: Serves as a precursor for synthesizing specialized ligands used in transition metal catalysis and cross-coupling reactions.
• Material Science: Employed in the research and development of organic electronic materials, such as OLEDs and semiconductors.
• Chemical Biology: Utilized as a probe or labeling agent in biochemical research due to the reactivity of the iodine moiety.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the global life sciences industry.

Basic Information

Item	Details
Product Name	2-Fluoro-4-Iodopyridin-3-Ol
CAS No.	1227593-95-4
Molecular Formula	C5H3FINO
Molecular Weight	238.99 g/mol
Synonyms	3-Hydroxy-2-fluoro-4-iodopyridine; 4-Iodo-2-fluoropyridin-3-ol; 2-Fluoro-4-iodo-3-hydroxypyridine; 2-Fluoro-4-iodo-3-pyridinol; 1227593-95-4; FC1=C(I)C=C(O)N=C1
EINECS	Contact for details

Quality Control

Our 2-Fluoro-4-Iodopyridin-3-Ol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment. We support cGMP compliance for pharmaceutical applications and can tailor purity grades to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong bases and fluorides. For long-term storage, consider inert atmosphere conditions to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0% (Standard Grade)
Purity (HPLC)	≥98.0% / ≥99.0% (Higher Grades Available)
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.