Description

5-Bromo-6-Fluoropicolinonitrile is a high-value, multi-functional heterocyclic building block essential for advanced organic synthesis. Its core value lies in its unique halogenated pyridine structure, which enables precise molecular modifications in the development of novel active compounds. This intermediate is critically needed by research and development teams in the pharmaceutical and agrochemical industries for creating new drug candidates and crop protection agents.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in kinase inhibitor and antiviral research programs.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides, leveraging its halogenated structure for bioactivity.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in transition metal catalysis and organocatalysis.
• Material Science Research: Employed in the synthesis of functionalized organic molecules for electronic materials and liquid crystals.
• Chemical Biology Probes: Utilized to build molecular probes for studying enzyme function and biological pathways.
• Custom Synthesis and Contract Manufacturing: A critical starting material for custom synthesis houses and CDMOs serving the life sciences sector.

Basic Information

Product Name	5-Bromo-6-Fluoropicolinonitrile
CAS No.	1227590-07-9
Molecular Formula	C6H2BrFN2
Molecular Weight	200.99 g/mol
Synonyms	6-Fluoro-5-bromopicolinonitrile; 5-Bromo-6-fluoro-2-cyanopyridine; 2-Cyano-5-bromo-6-fluoropyridine; 5-Bromo-6-fluoropyridine-2-carbonitrile; Picolinonitrile, 5-bromo-6-fluoro-; 1227590-07-9 (CAS); 5-Br-6-F-Pyridine-2-CN
EINECS	Contact for details

Quality Control

Our 5-Bromo-6-Fluoropicolinonitrile is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity for research and production use. Each lot undergoes comprehensive analytical characterization, including HPLC, NMR, and MS, to confirm identity and purity. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storage under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.