Description

3-Bromo-5-Chloropyridine-2-Carbaldehyde is a high-purity, multi-functional halogenated pyridine derivative that serves as a critical building block in advanced organic synthesis. Its unique structure, featuring both bromo and chloro substituents adjacent to an aldehyde group, makes it a versatile and highly reactive intermediate for constructing complex molecular architectures. This compound is essential for research and development chemists in the pharmaceutical, agrochemical, and material science industries, where it is used to create novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for kinase inhibitors, antiviral agents, and other small-molecule therapeutics.
• Agrochemical Synthesis: Used to develop novel herbicides, fungicides, and insecticides, leveraging its halogenated pyridine core for bioactivity.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in transition metal catalysis and organometallic chemistry.
• Material Science Research: Employed in the synthesis of organic electronic materials, such as ligands for OLEDs and conductive polymers.
• Chemical Biology Probes: Utilized to build molecular probes and tags for studying biological processes and protein interactions.
• Custom Synthesis and Scale-up: A fundamental building block for contract research organizations (CROs) and custom synthesis manufacturers for client-specific projects.

Basic Information

Product Name	3-Bromo-5-Chloropyridine-2-Carbaldehyde
CAS No.	1227588-49-9
Molecular Formula	C6H3BrClNO
Molecular Weight	220.45 g/mol
Synonyms	5-Chloro-3-bromopyridine-2-carboxaldehyde; 2-Bromo-6-chloropyridine-3-carbaldehyde; 3-Bromo-5-chloro-2-pyridinecarboxaldehyde; 2-Pyridinecarboxaldehyde, 3-bromo-5-chloro-; 3-Bromo-5-chloropicolinaldehyde; 5-Chloro-3-bromopicolinaldehyde; 2-Formyl-3-bromo-5-chloropyridine
EINECS	Contact for details

Quality Control

Our 3-Bromo-5-Chloropyridine-2-Carbaldehyde is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, documenting all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for your most demanding synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is light-sensitive (store away from light) and may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if necessary for long-term storage. Keep away from strong acids/bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.