Description

4-Fluoro-3-Methylpyridin-2-Amine is a high-purity, fluorinated pyridine derivative serving as a critical building block in advanced organic synthesis. This compound is valued for its unique molecular scaffold, which introduces both fluorine and an amine functional group to modulate the physicochemical and biological properties of target molecules. It is primarily sought by research and development teams in the pharmaceutical and agrochemical industries for the creation of novel active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in kinase inhibitor and central nervous system (CNS) drug discovery programs.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the fluorine atom enhances bioavailability and metabolic stability.
• Material Science Research: Employed as a precursor for synthesizing specialized ligands, catalysts, and functionalized polymers.
• Chemical Biology & Proteomics: Serves as a versatile building block for creating molecular probes and tool compounds to study biological pathways.
• Custom Synthesis & Contract Manufacturing: An essential starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Product Name	4-Fluoro-3-Methylpyridin-2-Amine
CAS No.	1227586-61-9
Molecular Formula	C6H7FN2
Molecular Weight	126.13 g/mol
Synonyms	2-Amino-4-fluoro-3-methylpyridine; 3-Methyl-4-fluoropyridin-2-amine; 4-Fluoro-3-methyl-2-pyridinamine; 4-Fluoro-3-methyl-2-aminopyridine; 2-Pyridinamine, 4-fluoro-3-methyl-
EINECS	Contact for details

Quality Control

Our 4-Fluoro-3-Methylpyridin-2-Amine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the stringent requirements for research and development applications. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from incompatible materials. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.