Description

5-Bromo-2-Bromomethyl-3-(Trifluoromethyl)Pyridine is a high-value, multi-functional halogenated pyridine derivative that serves as a critical building block in advanced organic synthesis. Its molecular structure, featuring both bromine substituents and a trifluoromethyl group, makes it an exceptionally versatile intermediate for introducing specific functionalities into target molecules. This compound is primarily sought after by research and development chemists in the pharmaceutical and agrochemical industries for the creation of novel active ingredients and complex chemical entities.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, oncology, and anti-infective therapies.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, where the trifluoromethyl and bromine groups enhance biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in transition metal catalysis and cross-coupling reactions, such as Suzuki and Buchwald-Hartwig aminations.
• Material Science Research: Employed in the synthesis of functionalized polymers, liquid crystals, and organic electronic materials due to its electron-withdrawing characteristics.
• Custom Synthesis and Contract Manufacturing: A vital reagent for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) working on proprietary client molecules.
• Chemical Biology & Proteomics: Can be utilized to create molecular probes and tags for studying biological systems and protein interactions.

Basic Information

Product Name	5-Bromo-2-Bromomethyl-3-(Trifluoromethyl)Pyridine
CAS No.	1227585-37-6
Molecular Formula	C7H4Br2F3N
Molecular Weight	318.92 g/mol
Synonyms	2-(Bromomethyl)-5-bromo-3-(trifluoromethyl)pyridine; 5-Bromo-2-(bromomethyl)-3-(trifluoromethyl)pyridine; 3-(Trifluoromethyl)-5-bromo-2-bromomethylpyridine; 2-Bromomethyl-5-bromo-3-trifluoromethylpyridine; Pyridine, 5-bromo-2-(bromomethyl)-3-(trifluoromethyl)-; 1227585-37-6
EINECS	Contact for details

Quality Control

Our 5-Bromo-2-Bromomethyl-3-(Trifluoromethyl)Pyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for your most demanding research and scale-up projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is moisture-sensitive (hygroscopic) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation. Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.