Description

2-Chloro-5-(Trifluoromethyl)-4-Pyridinemethanol is a high-value fluorinated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its unique structure, featuring both chloro and trifluoromethyl substituents, makes it an essential intermediate for creating molecules with enhanced biological activity and physicochemical properties. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, where the trifluoromethyl group improves lipophilicity and metabolic stability.
• Material Science Research: Serves as a monomer or functionalization agent in the creation of specialty polymers and liquid crystals with specific electronic or optical properties.
• Chemical Biology & Proteomics: Employed as a versatile scaffold for designing molecular probes, enzyme inhibitors, and labeled compounds for diagnostic applications.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Item	Details
Product Name	2-Chloro-5-(Trifluoromethyl)-4-Pyridinemethanol
CAS No.	1227585-35-4
Molecular Formula	C7H5ClF3NO
Molecular Weight	211.57 g/mol
Synonyms	(2-Chloro-5-(trifluoromethyl)pyridin-4-yl)methanol; 4-Pyridinemethanol, 2-chloro-5-(trifluoromethyl)-; 2-Chloro-5-trifluoromethyl-4-pyridylmethanol; 2-Chloro-5-(trifluoromethyl)-4-hydroxymethylpyridine; 2-Chloro-5-(trifluoromethyl)pyridine-4-methanol; 2-Chloro-5-(trifluoromethyl)-4-pyridylcarbinol
EINECS	Contact for details

Quality Control

Every batch of 2-Chloro-5-(Trifluoromethyl)-4-Pyridinemethanol is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your most demanding synthesis projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.