Description

2-Bromo-6-(Chloromethyl)-3-Fluoropyridine is a high-value, multi-functional halogenated pyridine derivative serving as a critical building block in advanced organic synthesis. Its molecular architecture, featuring bromine, chlorine, and fluorine substituents on the pyridine ring, makes it an exceptionally versatile intermediate for constructing complex molecules. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients, including potential drug candidates and crop protection agents.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules targeting central nervous system (CNS) disorders, oncology, and anti-infective therapies.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, where the halogenated pyridine core contributes to biological activity and metabolic stability.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in transition metal catalysis and asymmetric synthesis.
• Material Science Research: Employed in the synthesis of functionalized polymers, liquid crystals, and organic electronic materials due to its modifiable halogen sites.
• Custom Synthesis and Contract Manufacturing: A vital reagent for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) working on proprietary client molecules.

Basic Information

Product Name	2-Bromo-6-(Chloromethyl)-3-Fluoropyridine
CAS No.	1227584-96-4
Molecular Formula	C6H4BrClFN
Molecular Weight	224.46 g/mol
Synonyms	2-Bromo-6-(chloromethyl)-3-fluoropyridine; 3-Fluoro-2-bromo-6-chloromethylpyridine; 6-(Chloromethyl)-2-bromo-3-fluoropyridine; (2-Bromo-3-fluoro-6-pyridinyl)methyl chloride; Pyridine, 2-bromo-6-(chloromethyl)-3-fluoro-; 1227584-96-4
EINECS	Contact for details

Quality Control

Every batch of 2-Bromo-6-(Chloromethyl)-3-Fluoropyridine is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for sensitive synthetic applications. A detailed Certificate of Analysis (COA) is supplied with each shipment, reporting key parameters such as purity (by HPLC/NMR), identity confirmation, and impurity profiles. Our quality assurance protocols are designed to support cGMP (current Good Manufacturing Practice) compliance for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.