Description

2,3-Difluoro-4-Hydroxypyridine is a high-value fluorinated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its unique structure, featuring both fluorine atoms and a hydroxyl group on the pyridine ring, makes it an essential intermediate for creating complex molecules with tailored properties. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical industries for developing new active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in fluorinated drug candidates targeting CNS disorders, oncology, and anti-infectives.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the fluorine atoms enhance biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in coordination chemistry and catalysis, useful in asymmetric synthesis and material science.
• Material Science Research: Employed in the synthesis of functionalized polymers, liquid crystals, and electronic materials that require fluorinated aromatic components.
• Chemical Biology Probes: Utilized as a building block for fluorescent tags, enzyme inhibitors, and other molecular probes in diagnostic and biochemical research.

Basic Information

Product Name	2,3-Difluoro-4-Hydroxypyridine
CAS No.	1227579-00-1
Molecular Formula	C5H3F2NO
Molecular Weight	131.08 g/mol
Synonyms	4-Hydroxy-2,3-difluoropyridine; 2,3-Difluoropyridin-4-ol; 2,3-Difluoro-4-pyridinol; 4-Pyridinol, 2,3-difluoro-; Difluorohydroxypyridine
EINECS	Contact for details

Quality Control

Every batch of 2,3-Difluoro-4-Hydroxypyridine is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Due to its sensitivity to strong alkali and potential reactivity with fluorides, keep away from incompatible materials. Keep container tightly sealed to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.