Description

4-Bromo-3-Methyl-1,2-Dihydropyridin-2-One is a high-purity brominated heterocyclic building block of significant interest in advanced organic synthesis. This compound is valued for its role as a versatile intermediate in the development of novel pharmacologically active molecules. It is primarily sought by research and development teams in the pharmaceutical and agrochemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other small molecule therapeutics.
• Agrochemical Research: Used in the synthesis of novel crop protection agents and herbicides, leveraging its halogenated pyridone structure.
• Chemical Synthesis Building Block: Serves as a versatile precursor for further functionalization via cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) or nucleophilic substitution.
• Material Science Research: Investigated as a monomer or functional component in the development of specialty polymers and advanced organic materials.
• Academic & Contract Research: Employed in university and CRO laboratories for methodological studies and the discovery of new chemical entities.

Basic Information

Product Name	4-Bromo-3-Methyl-1,2-Dihydropyridin-2-One
CAS No.	1227578-99-5
Molecular Formula	C6H6BrNO
Molecular Weight	188.02 g/mol
Synonyms	4-Bromo-3-methyl-2-pyridone; 4-Bromo-3-methyl-1H-pyridin-2-one; 3-Methyl-4-bromo-2(1H)-pyridinone; 4-Bromo-3-methylpyridin-2(1H)-one; 2(1H)-Pyridinone, 4-bromo-3-methyl-; 4-Bromo-3-methyl-1,2-dihydro-2-pyridone
EINECS	Contact for details

Quality Control

Our 4-Bromo-3-Methyl-1,2-Dihydropyridin-2-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR/IR for structural confirmation, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.