Description

4-Bromo-6-Fluoropyridin-3-Ol is a high-purity halogenated pyridine derivative serving as a critical building block in advanced organic synthesis. This compound matters for its unique substitution pattern, which provides a versatile chemical handle for constructing complex molecules, particularly in the pharmaceutical and agrochemical sectors. It is primarily needed by research chemists and process development scientists working on active pharmaceutical ingredients (APIs), crop protection agents, and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly in kinase inhibitor and central nervous system (CNS) therapeutic research.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides, leveraging its halogenated pyridine core.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in transition metal catalysis and coordination chemistry.
• Material Science Research: Employed in the synthesis of organic electronic materials and liquid crystals due to its electron-withdrawing halogen substituents.
• Custom Synthesis and Contract Manufacturing: A fundamental starting material for custom synthesis projects and scale-up processes in fine chemical production.
• Academic and R&D Laboratories: Utilized in methodological studies and the exploration of new chemical reactions involving halogenated heterocycles.

Basic Information

Product Name	4-Bromo-6-Fluoropyridin-3-Ol
CAS No.	1227578-23-5
Molecular Formula	C5H3BrFNO
Molecular Weight	191.99 g/mol
Synonyms	3-Hydroxy-4-bromo-6-fluoropyridine; 4-Bromo-6-fluoro-3-hydroxypyridine; 4-Bromo-6-fluoro-3-pyridinol; 6-Fluoro-4-bromopyridin-3-ol; 4-Bromo-6-fluoropyridin-3-ol; 1227578-23-5
EINECS	Contact for details

Quality Control

Our 4-Bromo-6-Fluoropyridin-3-Ol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) documenting all critical quality attributes are available upon request to support your regulatory and quality assurance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials. Due to its light-sensitive nature, prolonged exposure to light should be avoided.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.