Description

2-Chloro-4-Fluoro-3-(Trifluoromethyl)Pyridine is a high-value, multi-functional halogenated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its unique structure, featuring chlorine, fluorine, and a trifluoromethyl group on the pyridine ring, makes it an essential intermediate for creating compounds with tailored biological activity and physical properties. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the development of new active ingredients.

Application

• Pharmaceutical Intermediate: Key synthon for the research and development of novel active pharmaceutical ingredients (APIs), particularly in areas like kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides, where the fluorine and trifluoromethyl groups enhance bioavailability and environmental stability.
• Material Science Research: Serves as a precursor for functionalized ligands and monomers in the development of specialty polymers and advanced materials.
• Chemical Research & Development: A versatile building block for medicinal chemistry and process chemistry, enabling structure-activity relationship (SAR) studies and route scouting.

Basic Information

Product Name	2-Chloro-4-Fluoro-3-(Trifluoromethyl)Pyridine
CAS No.	1227574-46-0
Molecular Formula	C6H2ClF4N
Molecular Weight	199.53 g/mol
Synonyms	2-Chloro-4-fluoro-3-(trifluoromethyl)pyridine; 3-(Trifluoromethyl)-2-chloro-4-fluoropyridine; 2-Chloro-4-fluoro-3-trifluoromethylpyridine; Pyridine, 2-chloro-4-fluoro-3-(trifluoromethyl)-; 1227574-46-0
EINECS	Contact for details

Quality Control

Our production of 2-Chloro-4-Fluoro-3-(Trifluoromethyl)Pyridine adheres to stringent internal quality standards to ensure batch-to-batch consistency and high purity for research and scale-up applications. Each lot is characterized using advanced analytical techniques including GC, HPLC, and NMR. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials such as strong bases and reducing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (by HPLC/GC)	≥ 97.0% (Typical 98-99%)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.