Description

6-Chloro-2-Fluoro-3-Methoxypyridine is a high-value fluorinated pyridine derivative, a key heterocyclic building block prized for its unique substitution pattern. This compound is essential for introducing both halogen and methoxy functionalities into complex molecular architectures, enabling precise modulation of biological activity and physicochemical properties. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of advanced intermediates and active ingredients.

Application

• Pharmaceutical Intermediate: A critical synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in kinase inhibitor and central nervous system (CNS) drug discovery programs.
• Agrochemical Synthesis: Used in the research and production of modern pesticides and herbicides, where the fluorine atom enhances metabolic stability and bioavailability.
• Material Science Research: Serves as a precursor for functionalized ligands and organic electronic materials due to its electron-withdrawing characteristics.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes and tags for studying biological systems and mechanisms.
• Custom Synthesis & Contract Manufacturing: A fundamental building block for custom synthesis services catering to advanced R&D projects across multiple sectors.

Basic Information

Product Name	6-Chloro-2-Fluoro-3-Methoxypyridine
CAS No.	1227573-07-0
Molecular Formula	C6H5ClFNO
Molecular Weight	161.56 g/mol
Synonyms	2-Fluoro-6-chloro-3-methoxypyridine; 3-Methoxy-6-chloro-2-fluoropyridine; 6-Chloro-2-fluoro-3-methoxypyridine; 2-Fluoro-3-methoxy-6-chloropyridine; 6-Chloro-2-fluoropyridin-3-yl methyl ether; Pyridine, 6-chloro-2-fluoro-3-methoxy-; 1227573-07-0
EINECS	Contact for details

Quality Control

Our 6-Chloro-2-Fluoro-3-Methoxypyridine is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide detailed Certificates of Analysis (COA) with each shipment, confirming compliance with customer specifications and supporting regulatory filings for pharmaceutical and agrochemical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong acids/bases and oxidizing agents. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥98.0% (Standard Grade)
Purity (GC)	≥98.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.