Description

2-(5-Chloro-3-Fluoropyridin-2-Yl)Acetonitrile is a high-value halogenated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its molecular structure, featuring both chloro and fluoro substituents on the pyridine ring, makes it an essential intermediate for constructing complex molecules with tailored properties. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, insecticides, and fungicides, leveraging the bioactivity of the fluoropyridine moiety.
• Material Science Research: Serves as a monomer or functionalization agent in the creation of specialty polymers and liquid crystals.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes and tags for diagnostic and research applications.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.

Basic Information

Product Name	2-(5-Chloro-3-Fluoropyridin-2-Yl)Acetonitrile
CAS No.	1227572-25-9
Molecular Formula	C7H4ClFN2
Molecular Weight	170.57 g/mol
Synonyms	(5-Chloro-3-fluoropyridin-2-yl)acetonitrile; 2-(5-Chloro-3-fluoropyridin-2-yl)ethanenitrile; 2-(5-Chloro-3-fluoro-2-pyridinyl)acetonitrile; 2-Pyridineacetonitrile, 5-chloro-3-fluoro-; Acetonitrile, (5-chloro-3-fluoro-2-pyridinyl)-; 1227572-25-9; 5-Chloro-3-fluoro-2-pyridineacetonitrile
EINECS	Contact for details

Quality Control

Our production of 2-(5-Chloro-3-Fluoropyridin-2-Yl)Acetonitrile adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) are available upon request, detailing key parameters such as purity, identity, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area. Recommended storage temperature is between 2°C and 8°C for long-term stability. The compound is moisture-sensitive; keep the container tightly sealed under an inert atmosphere if specified.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.