Description

(2-Chloro-3-Methoxy-Pyridin-4-Yl)-Methanol is a high-purity pyridine derivative building block essential for advanced organic synthesis. This compound matters as a critical intermediate for constructing complex molecules in pharmaceutical and agrochemical research, offering a versatile handle for further functionalization. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for developing new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in kinase inhibitor and central nervous system (CNS) drug discovery.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides, fungicides, and insecticides, leveraging its halogenated pyridine core.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in metal-catalyzed cross-coupling reactions and other catalytic processes.
• Material Science Research: Employed in the synthesis of functionalized organic molecules for advanced materials, such as organic semiconductors or metal-organic frameworks (MOFs).
• Custom Synthesis and Contract Manufacturing: A valuable starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Product Name	(2-Chloro-3-Methoxy-Pyridin-4-Yl)-Methanol
CAS No.	1227564-18-2
Molecular Formula	C7H8ClNO2
Molecular Weight	173.60 g/mol
Synonyms	4-(Hydroxymethyl)-2-chloro-3-methoxypyridine; 2-Chloro-3-methoxy-4-pyridinemethanol; (2-Chloro-3-methoxypyridin-4-yl)methanol; 2-Chloro-3-methoxyisonicotinyl alcohol; 2-Chloro-3-methoxypyridine-4-methanol; 4-Pyridinemethanol, 2-chloro-3-methoxy-; 2-Chloro-3-methoxy-4-hydroxymethylpyridine
EINECS	Contact for details

Quality Control

Our (2-Chloro-3-Methoxy-Pyridin-4-Yl)-Methanol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment supports applications requiring high-purity intermediates under cGMP or ISO 9001 frameworks.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). This material is moisture-sensitive (hygroscopic); keep the container tightly sealed under an inert atmosphere if necessary. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥97.0%
Purity (HPLC, Area%)	≥98.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.