Description

6-Amino-2-Trifluoromethyl-Pyridin-3-Ol is a high-value trifluoromethylated pyridine derivative, a key building block in modern synthetic chemistry. Its structure, featuring both an amino and a hydroxyl group on the pyridine ring adjacent to a trifluoromethyl group, makes it a versatile intermediate for constructing complex molecules with enhanced properties. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting central nervous system (CNS) disorders, anti-infectives, and oncology.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides, where the trifluoromethyl group often improves metabolic stability and bioavailability.
• Material Science Research: Serves as a building block for creating specialty polymers, liquid crystals, and organic electronic materials due to its unique electronic properties.
• Chemical Biology & Proteomics: Employed as a molecular scaffold or labeling agent in the design of chemical probes and enzyme inhibitors for biological research.
• Custom Synthesis & Contract Manufacturing: A key starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Product Name	6-Amino-2-Trifluoromethyl-Pyridin-3-Ol
CAS No.	1227515-32-3
Molecular Formula	C7H5F3N2O
Molecular Weight	178.12 g/mol
Synonyms	3-Hydroxy-6-amino-2-(trifluoromethyl)pyridine; 2-(Trifluoromethyl)-3-hydroxy-6-aminopyridine; 6-Amino-2-(trifluoromethyl)pyridin-3-ol; 6-Amino-α,α,α-trifluoro-3-pyridinol; 3-Pyridinol, 6-amino-2-(trifluoromethyl)-
EINECS	Contact for details

Quality Control

Our 6-Amino-2-Trifluoromethyl-Pyridin-3-Ol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Assay	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.