Description

2-Amino-6-(Trifluoromethyl)Pyridin-3-Ol is a high-value, multi-functional pyridine derivative characterized by its amino and trifluoromethyl substituents, making it a versatile building block for advanced synthesis. This compound is essential for research and development in life sciences, where its unique structure enables the creation of novel molecules with tailored properties. It is primarily sought after by pharmaceutical, agrochemical, and specialty chemical manufacturers for applications in drug discovery, crop protection, and material science.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in oncology, neurology, and anti-infective therapeutic areas.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, leveraging the bioactivity-enhancing trifluoromethyl group.
• Ligand and Catalyst Development: Serves as a precursor for creating novel ligands in transition metal catalysis and organocatalysis for asymmetric synthesis.
• Material Science Research: Employed in the synthesis of functionalized polymers, liquid crystals, and organic electronic materials.
• Chemical Biology Probe: Utilized in medicinal chemistry to create molecular probes for studying enzyme mechanisms and biological pathways.
• Custom Synthesis and Contract Manufacturing: A critical starting material for custom synthesis projects and scale-up services for specialized chemical entities.

Basic Information

Product Name	2-Amino-6-(Trifluoromethyl)Pyridin-3-Ol
CAS No.	1227515-04-9
Molecular Formula	C6H5F3N2O
Molecular Weight	178.11 g/mol
Synonyms	3-Hydroxy-2-amino-6-(trifluoromethyl)pyridine; 2-Amino-6-(trifluoromethyl)-3-pyridinol; 6-(Trifluoromethyl)-3-pyridinol-2-amine; 2-Amino-3-hydroxy-6-(trifluoromethyl)pyridine; 2-Amino-6-trifluoromethylpyridin-3-ol; 1227515-04-9; 2-Amino-6-(trifluoromethyl)-3-hydroxypyridine
EINECS	Contact for details

Quality Control

Our 2-Amino-6-(Trifluoromethyl)Pyridin-3-Ol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide full traceability and Certificates of Analysis (COA) are available for every shipment, confirming compliance with agreed specifications. Our quality commitment supports applications requiring high-purity intermediates under cGMP or ISO 9001 frameworks.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.