Description

4-Hydroxy-2-Methoxy-6-(Trifluoromethyl)Pyridine is a high-value, multi-functional heterocyclic building block characterized by its unique trifluoromethyl and methoxy substituents. This compound is essential for researchers and manufacturers seeking to incorporate fluorine atoms and specific steric/electronic profiles into advanced molecular architectures. It is primarily utilized in the pharmaceutical, agrochemical, and advanced materials sectors for the synthesis of novel active ingredients and functional intermediates.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in kinase inhibitors, anti-inflammatory agents, and central nervous system (CNS) drugs.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances biological activity and metabolic stability.
• Ligand & Catalyst Development: Serves as a precursor for creating specialized ligands in transition metal catalysis and organocatalysis for asymmetric synthesis.
• Material Science Research: Employed in the synthesis of organic electronic materials, liquid crystals, and polymers requiring specific fluorine-containing motifs.
• Chemical Biology & Proteomics: Acts as a versatile scaffold for designing molecular probes and enzyme inhibitors in biochemical research.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Product Name	4-Hydroxy-2-Methoxy-6-(Trifluoromethyl)Pyridine
CAS No.	1227513-61-2
Molecular Formula	C7H6F3NO2
Molecular Weight	193.12 g/mol
Synonyms	6-(Trifluoromethyl)-2-methoxypyridin-4-ol; 2-Methoxy-6-(trifluoromethyl)pyridin-4-ol; 4-Hydroxy-2-methoxy-6-trifluoromethylpyridine; 4-Hydroxy-2-methoxy-6-(trifluoromethyl)pyridine; 4-Pyridinol, 2-methoxy-6-(trifluoromethyl)-
EINECS	Contact for details

Quality Control

Our 4-Hydroxy-2-Methoxy-6-(Trifluoromethyl)Pyridine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with agreed specifications. Our quality commitment supports applications in GMP and ISO-regulated environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong bases and fluorinating agents. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.