Description

2-Iodo-1H-Pyrrolo[2,3-B]Pyridine is a high-value halogenated heterocyclic building block, specifically an iodinated pyrrolopyridine derivative. This compound is essential for advanced pharmaceutical research and development, serving as a key intermediate in the synthesis of complex bioactive molecules. It is primarily utilized by medicinal chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for constructing novel drug candidates and functional materials.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of kinase inhibitors and other targeted therapeutic agents.
• Medicinal Chemistry: Used in structure-activity relationship (SAR) studies and lead optimization campaigns due to its versatile reactivity.
• Agrochemical Research: Serves as a building block for developing new active ingredients with potential herbicidal or insecticidal properties.
• Material Science: Employed in the creation of organic electronic materials and ligands for catalytic systems.
• Cross-Coupling Reactions: Acts as a pivotal substrate in palladium-catalyzed reactions such as Suzuki, Negishi, and Sonogashira couplings for carbon-carbon bond formation.
• Chemical Biology: Used in the design and synthesis of molecular probes for studying biological pathways and protein functions.

Basic Information

Product Name	2-Iodo-1H-Pyrrolo[2,3-B]Pyridine
CAS No.	1227270-32-7
Molecular Formula	C7H5IN2
Molecular Weight	244.03 g/mol
Synonyms	2-Iodo-1H-pyrrolo[2,3-b]pyridine; 2-Iodo-7-azaindole; 2-Iodo-1H-pyrrolo[2,3-b]pyridine; 1H-Pyrrolo[2,3-b]pyridine, 2-iodo-; 2-Iodo-1H-7-azaindole; 2-Iodopyrrolo[2,3-b]pyridine; 2-Iodo-7-aza-indole
EINECS	Contact for details

Quality Control

Our 2-Iodo-1H-Pyrrolo[2,3-B]Pyridine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat and incompatible materials. Due to its light-sensitive nature, handling and storage should minimize exposure to direct light.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.