Description

Methyl 2-Amino-5-Cyanonicotinate CAS NO 1227048-81-8 is a high-value pyridine derivative and a versatile building block in advanced organic synthesis. Its unique structure, featuring both amino and cyano substituents, makes it a critical intermediate for constructing complex heterocyclic systems. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, where it is used to create novel active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly kinase inhibitors and other targeted therapies.
• Agrochemical Synthesis: Building block for developing new generation herbicides, fungicides, and insecticides with improved efficacy.
• Material Science Research: Used in the development of organic semiconductors, ligands for catalysis, and advanced polymeric materials.
• Chemical Biology Probes: Serves as a scaffold for creating fluorescent tags and molecular probes for diagnostic applications.
• Academic & Contract Research: Fundamental reagent for methodological development and exploration of new chemical reactions in academic and CRO settings.

Basic Information

Product Name	Methyl 2-Amino-5-Cyanonicotinate
CAS No.	1227048-81-8
Molecular Formula	C8H7N3O2
Molecular Weight	177.16 g/mol
Synonyms	2-Amino-5-cyano-3-pyridinecarboxylic acid methyl ester; Methyl 2-amino-5-cyanopyridine-3-carboxylate; 3-Pyridinecarboxylic acid, 2-amino-5-cyano-, methyl ester; 5-Cyano-2-aminonicotinic acid methyl ester; 2-Amino-5-cyanonicotinic acid methyl ester; Methyl 5-cyano-2-aminonicotinate
EINECS	Contact for details

Quality Control

Our Methyl 2-Amino-5-Cyanonicotinate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, IR). We provide full traceability and detailed Certificates of Analysis (COA) with every shipment to ensure compliance with your research and development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.