Description

4-(4-N.n-Dimethylsulfamoyl)Piperazino-1-Bromobenzene is a high-purity, advanced pharmaceutical intermediate featuring a bromobenzene core functionalized with a piperazine and dimethylsulfamoyl group. This compound is valued for its role as a critical building block in the synthesis of complex active pharmaceutical ingredients (APIs), particularly in medicinal chemistry research and development. It is essential for pharmaceutical manufacturers and R&D organizations focused on developing novel therapeutic agents, including kinase inhibitors and other small-molecule drugs.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of complex drug candidates and active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies for new drug discovery programs.
• Kinase Inhibitor Development: Serves as a crucial scaffold in the design and synthesis of targeted kinase inhibitor molecules.
• Chemical Synthesis Building Block: Employed in organic synthesis to introduce the functionalized piperazino-bromobenzene moiety into larger molecular architectures.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for the pharmaceutical industry.

Basic Information

Product Name	4-(4-N.n-Dimethylsulfamoyl)Piperazino-1-Bromobenzene
CAS No.	1226808-59-8
Molecular Formula	C13H19BrN4O2S
Molecular Weight	375.29 g/mol
Synonyms	1-Bromo-4-[4-(dimethylsulfamoyl)piperazin-1-yl]benzene; 4-(4-(Dimethylsulfamoyl)piperazin-1-yl)-1-bromobenzene; 4-Bromo-N,N-dimethyl-1-piperazinebenzenesulfonamide; 1-Bromo-4-(4-(N,N-dimethylsulfamoyl)piperazin-1-yl)benzene; 4-(4-(Dimethylsulfamoyl)piperazino)bromobenzene
EINECS	Contact for details

Quality Control

Our 4-(4-N.n-Dimethylsulfamoyl)Piperazino-1-Bromobenzene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications and test results are provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.