Description

2-(Boc-Amino)-4-(Aminomethyl)Pyridine Dihydrochloride is a protected amino-pyridine derivative, primarily serving as a critical building block in organic synthesis. Its value lies in providing a versatile scaffold for constructing complex molecules, particularly in pharmaceutical research and development. This compound is essential for medicinal chemists and process development scientists working in drug discovery, agrochemical research, and advanced material science.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for kinase inhibitors and other small-molecule therapeutics.
• Peptide Mimetics & Conjugation: Used to introduce pyridine-based functionalities and protected amine handles into peptides and bioconjugates.
• Ligand Synthesis: Serves as a starting material for creating chelating ligands and catalysts used in asymmetric synthesis and metal-organic frameworks (MOFs).
• Agrochemical Research: Employed in the development of novel herbicides, fungicides, and plant growth regulators.
• Chemical Biology Probes: Utilized to create molecular probes for studying enzyme function and biological pathways.
• Custom Synthesis & Scale-Up: A fundamental unit for contract research organizations (CROs) and CDMOs performing custom synthesis from milligram to kilogram scale.

Basic Information

Product Name	2-(Boc-Amino)-4-(Aminomethyl)Pyridine Dihydrochloride
CAS No.	1226776-85-7
Molecular Formula	C12H20Cl2N3O2
Molecular Weight	309.21 g/mol
Synonyms	2-[(tert-Butoxycarbonyl)amino]-4-(aminomethyl)pyridine dihydrochloride; 4-(Aminomethyl)-2-[(tert-butoxycarbonyl)amino]pyridine dihydrochloride; 2-(Boc-amino)-4-(aminomethyl)pyridine HCl salt; N-Boc-2-amino-4-(aminomethyl)pyridine dihydrochloride; tert-Butyl [4-(aminomethyl)pyridin-2-yl]carbamate dihydrochloride; 2-(tert-Butoxycarbonylamino)-4-(aminomethyl)pyridine dihydrochloride; Boc-2-A-4-AMPy•2HCl
EINECS	Contact for details

Quality Control

Our 2-(Boc-Amino)-4-(Aminomethyl)Pyridine Dihydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed specifications are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccant and inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.