Description

2-Methyl-5-Piperazin-1-Yl-Oxazole-4-Carbonitrile is a heterocyclic organic compound featuring a piperazine-substituted oxazole core. This high-purity intermediate is critical for pharmaceutical research and development, particularly in the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries seeking to build complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key building block in the research and synthesis of potential drug candidates, especially for central nervous system (CNS) and oncology targets.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides due to its heterocyclic scaffold.
• Chemical Biology Probe Synthesis: Serves as a precursor for creating molecular tools to study biological pathways and protein functions.
• Ligand and Catalyst Development: Employed in the design of novel ligands for metal catalysis and organocatalysts.
• Material Science Research: Investigated as a monomer or additive for specialty polymers with specific electronic or thermal properties.
• Custom Synthesis and Contract Manufacturing: Supplied for bespoke chemical synthesis projects requiring high-purity, complex intermediates.

Basic Information

Product Name	2-Methyl-5-Piperazin-1-Yl-Oxazole-4-Carbonitrile
CAS No.	1226452-86-3
Molecular Formula	C9H12N4O
Molecular Weight	192.22 g/mol
Synonyms	2-Methyl-5-(piperazin-1-yl)-1,3-oxazole-4-carbonitrile; 5-(Piperazin-1-yl)-2-methyl-1,3-oxazole-4-carbonitrile; 4-Cyano-2-methyl-5-piperazinyloxazole; 2-Methyl-5-(1-piperazinyl)-4-oxazolecarbonitrile; Oxazole-4-carbonitrile, 2-methyl-5-(1-piperazinyl)-; 1226452-86-3
EINECS	Contact for details

Quality Control

Our 2-Methyl-5-Piperazin-1-Yl-Oxazole-4-Carbonitrile is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the high standards required for research and development. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under dry, inert conditions to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.