Description

3-Propionyl-Piperidine-1-Carboxylic Acid tert-Butyl Ester is a high-value piperidine derivative and a crucial protected intermediate in advanced organic synthesis. Its core value lies in providing a versatile scaffold for constructing complex molecules, particularly in pharmaceutical research and development. This compound is essential for medicinal chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries who require reliable, high-purity building blocks.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly those targeting the central nervous system (CNS) and other therapeutic areas.
• Medicinal Chemistry Research: Used in hit-to-lead optimization and structure-activity relationship (SAR) studies to explore new chemical entities.
• Process Chemistry Development: Serves as a critical intermediate in scaling up synthetic routes from laboratory to pilot plant and commercial production.
• Agrochemical Synthesis: Intermediate in the development of new crop protection agents and pesticides.
• Custom Synthesis & Contract Manufacturing: A starting material for custom synthesis projects and the production of specialized fine chemicals.
• Academic Research: Used in universities and research institutes for methodological development and the study of new organic reactions.

Basic Information

Product Name	3-Propionyl-Piperidine-1-Carboxylic Acid tert-Butyl Ester
CAS No.	1226294-61-6
Molecular Formula	C14H25NO3
Molecular Weight	255.35 g/mol
Synonyms	1-Boc-3-propionylpiperidine; tert-Butyl 3-propionylpiperidine-1-carboxylate; 3-Propionyl-1-Boc-piperidine; 1-(tert-Butoxycarbonyl)-3-propionylpiperidine; Piperidine-1-carboxylic acid, 3-(1-oxopropyl)-, 1,1-dimethylethyl ester; 3-Propanoyl-1-Boc-piperidine; 3-Propionylpiperidine-1-carboxylic acid tert-butyl ester
EINECS	Contact for details

Quality Control

Our 3-Propionyl-Piperidine-1-Carboxylic Acid tert-Butyl Ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide full traceability and detailed Certificates of Analysis (COA) with every shipment. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your critical R&D and production processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere (e.g., nitrogen) after opening to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.