Description

2-[(3-Trifluoromethyl)Phenyl]Isonicotinic Acid CAS NO 1226291-45-7 is a high-value, multifunctional aromatic acid derivative featuring a trifluoromethylphenyl group. This compound serves as a critical advanced pharmaceutical intermediate (API) and a versatile building block in modern synthetic chemistry. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical sectors for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, inflammation, and metabolic diseases.
• Agrochemical Research: Used as a building block for developing new herbicides, fungicides, and insecticides, leveraging the bioactivity-enhancing properties of the trifluoromethyl group.
• Ligand Synthesis: Employed in the preparation of specialized ligands for catalysis and metal-organic frameworks (MOFs) due to its rigid, functionalized structure.
• Material Science: Serves as a monomer or additive in the development of advanced polymers with specific thermal or chemical resistance properties.
• Organic Synthesis Building Block: A versatile reagent for constructing complex heterocyclic compounds and for introducing the trifluoromethylphenyl moiety into target molecules.

Basic Information

Product Name	2-[(3-Trifluoromethyl)Phenyl]Isonicotinic Acid
CAS No.	1226291-45-7
Molecular Formula	C13H8F3NO2
Molecular Weight	267.21 g/mol
Synonyms	2-[3-(Trifluoromethyl)phenyl]pyridine-4-carboxylic acid; 4-Pyridinecarboxylic acid, 2-[3-(trifluoromethyl)phenyl]-; 2-(3-Trifluoromethylphenyl)isonicotinic acid; Isonicotinic acid, 2-[(3-trifluoromethyl)phenyl]-; 2-(α,α,α-Trifluoro-m-tolyl)isonicotinic acid
EINECS	Contact for details

Quality Control

Our 2-[(3-Trifluoromethyl)Phenyl]Isonicotinic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR/IR for structural confirmation, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.