Description

3-Ethyl-1-(4-Fluorophenyl)-1H-Pyrazol-5-Amine is a high-purity, specialized heterocyclic building block of significant interest in advanced organic synthesis. Its core value lies in its unique pyrazole scaffold substituted with a fluorine atom and an amine group, making it a versatile intermediate for constructing complex molecules. This compound is primarily needed by research institutions and pharmaceutical companies engaged in the development of new active pharmaceutical ingredients (APIs) and agrochemicals.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, and metabolic diseases.
• Agrochemical Research: Used in the development of new-generation pesticides and herbicides, where the fluorine atom can enhance biological activity and environmental stability.
• Material Science: Serves as a precursor for functionalized polymers and advanced organic materials with specific electronic or photophysical properties.
• Chemical Biology: Employed as a probe or linker in the design of molecules for studying biological pathways and protein interactions.
• Custom Synthesis: A critical starting material for contract research organizations (CROs) and CDMOs performing bespoke synthesis for client projects.

Basic Information

Product Name	3-Ethyl-1-(4-Fluorophenyl)-1H-Pyrazol-5-Amine
CAS No.	1226221-27-7
Molecular Formula	C11H12FN3
Molecular Weight	205.23 g/mol
Synonyms	5-Amino-3-ethyl-1-(4-fluorophenyl)-1H-pyrazole; 1-(4-Fluorophenyl)-3-ethyl-1H-pyrazol-5-amine; 3-Ethyl-1-(4-fluorophenyl)-1H-pyrazol-5-ylamine; 3-Ethyl-1-(p-fluorophenyl)-1H-pyrazol-5-amine; 1226221-27-7; 5-Amino-1-(4-fluorophenyl)-3-ethylpyrazole; 1H-Pyrazol-5-amine, 3-ethyl-1-(4-fluorophenyl)-
EINECS	Contact for details

Quality Control

Our 3-Ethyl-1-(4-Fluorophenyl)-1H-Pyrazol-5-Amine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our quality commitment aligns with cGMP standards for pharmaceutical intermediates, ensuring reliability for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.