Description

2-Bromo-6-Chloro-3-Methyl-5-Nitropyridine CAS NO 1225348-48-0 is a high-purity, multi-functional heterocyclic building block essential for advanced organic synthesis. Its unique halogenated and nitrated pyridine structure makes it a critical intermediate for constructing complex molecules with tailored properties. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for creating novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drug candidates targeting central nervous system (CNS) disorders and infectious diseases.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, leveraging its halogenated pyridine core for bioactivity.
• Material Science Research: Serves as a building block for creating functionalized ligands, organic semiconductors, and specialty polymers.
• Chemical Biology & Proteomics: Employed in the design of molecular probes, enzyme inhibitors, and bioconjugation reagents for biochemical research.
• Dye & Pigment Manufacturing: Acts as an intermediate for synthesizing complex heterocyclic dyes and colorants.

Basic Information

Product Name	2-Bromo-6-Chloro-3-Methyl-5-Nitropyridine
CAS No.	1225348-48-0
Molecular Formula	C6H4BrClN2O2
Molecular Weight	251.47 g/mol
Synonyms	2-Bromo-6-chloro-3-methyl-5-nitropyridine; 5-Nitro-2-bromo-6-chloro-3-picoline; 3-Methyl-5-nitro-2-bromo-6-chloropyridine; 2-Bromo-6-chloro-3-methyl-5-nitro-pyridine; Pyridine, 2-bromo-6-chloro-3-methyl-5-nitro-; 1225348-48-0; 2-Br-6-Cl-3-Me-5-NO2-Pyridine
EINECS	Contact for details

Quality Control

Our 2-Bromo-6-Chloro-3-Methyl-5-Nitropyridine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and batch-to-batch consistency suitable for sensitive R&D and scale-up processes. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive (store away from light) and should be handled under an inert atmosphere if prolonged exposure is expected.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.