Description

4-Methyl-4-(Pyridin-3-Yl)Pyrrolidin-2-One is a high-purity, advanced pharmaceutical intermediate featuring a unique pyrrolidinone scaffold fused with a pyridine moiety. This compound is of significant value for medicinal chemistry research and development, serving as a versatile building block for constructing novel bioactive molecules. It is primarily sought after by pharmaceutical R&D teams and fine chemical manufacturers engaged in the synthesis of potential drug candidates targeting the central nervous system and other therapeutic areas.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for neurological and psychiatric disorders.
• Medicinal Chemistry Research: Used in hit-to-lead and lead optimization campaigns to explore structure-activity relationships (SAR) around the pyrrolidinone core.
• Library Synthesis: Employed in the generation of diverse compound libraries for high-throughput screening (HTS) against various biological targets.
• Chemical Biology Probes: Serves as a precursor for developing molecular probes to study enzyme function or receptor interactions.
• Process Chemistry Development: Utilized in scaling up synthetic routes for potential drug candidates during preclinical and clinical development phases.

Basic Information

Product Name	4-Methyl-4-(Pyridin-3-Yl)Pyrrolidin-2-One
CAS No.	1225218-51-8
Molecular Formula	C10H12N2O
Molecular Weight	176.22 g/mol
Synonyms	4-Methyl-4-(3-pyridinyl)-2-pyrrolidinone; 4-(Pyridin-3-yl)-4-methylpyrrolidin-2-one; 3-Pyridinyl-4-methyl-2-pyrrolidinone; 4-Methyl-4-(3-pyridyl)pyrrolidin-2-one; 4-(3-Pyridinyl)-4-methyl-2-pyrrolidinone; 2-Pyrrolidinone, 4-methyl-4-(3-pyridinyl)-
EINECS	Contact for details

Quality Control

Our 4-Methyl-4-(Pyridin-3-Yl)Pyrrolidin-2-One is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide full traceability and detailed Certificates of Analysis (COA) with every shipment, supporting your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.