Description

tert-Butyl 4-cyclohexylpiperazine-1-carboxylate is a high-purity, protected piperazine derivative of significant importance in modern organic synthesis. This compound serves as a crucial pharmaceutical intermediate and building block for the development of novel active pharmaceutical ingredients (APIs). It is primarily utilized by research institutions and manufacturers in the pharmaceutical and fine chemical industries engaged in drug discovery and process chemistry.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of complex drug molecules, particularly those targeting central nervous system (CNS) disorders.
• API Development: Used in research and process development for new active pharmaceutical ingredients requiring a protected cyclohexylpiperazine moiety.
• Chemical Synthesis: Serves as a versatile precursor in organic synthesis for introducing the 4-cyclohexylpiperazine group into more complex molecular architectures.
• Medicinal Chemistry Research: Employed in structure-activity relationship (SAR) studies and library synthesis for lead optimization in drug discovery programs.
• Custom Synthesis: A starting material for contract research and manufacturing organizations (CROs/CMOs) producing specialized fine chemicals for clients.

Basic Information

Product Name	tert-Butyl 4-Cyclohexylpiperazine-1-Carboxylate
CAS No.	1224935-95-8
Molecular Formula	C15H28N2O2
Molecular Weight	268.40 g/mol
Synonyms	1-Boc-4-cyclohexylpiperazine; 4-Cyclohexyl-1-piperazinecarboxylic acid tert-butyl ester; tert-Butyl 4-cyclohexyl-1-piperazinecarboxylate; 1-(tert-Butoxycarbonyl)-4-cyclohexylpiperazine; Boc-4-cyclohexylpiperazine; N-Boc-4-cyclohexylpiperazine; 4-Cyclohexylpiperazine-1-carboxylic acid tert-butyl ester
EINECS	Contact for details

Quality Control

Our tert-Butyl 4-cyclohexylpiperazine-1-carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and identity. Certificates of Analysis (COA) detailing all specifications are provided to guarantee batch-to-batch consistency and support your regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.