Description

2-Chloro-5-(2H-Tetrazol-5-Yl)Pyridine is a high-value heterocyclic building block featuring a pyridine core substituted with both a chloro group and a tetrazole moiety. This compound matters as a versatile and critical intermediate in modern pharmaceutical and agrochemical research, enabling the synthesis of complex molecules with targeted biological activity. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical industry for the development of new active pharmaceutical ingredients (APIs), particularly in areas like hypertension and oncology.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of sartan-class antihypertensive drugs (ARBs) and other receptor antagonists.
• Agrochemical Research: Used as a building block for developing novel herbicides and pesticides with specific modes of action.
• Ligand Synthesis: Serves as a precursor for creating complex ligands in coordination chemistry and catalysis.
• Material Science: Potential monomer or additive in the development of specialty polymers and functional materials.
• Bioconjugation: The tetrazole group can be utilized in bioorthogonal chemistry for labeling and modifying biomolecules.

Basic Information

Product Name	2-Chloro-5-(2H-Tetrazol-5-Yl)Pyridine
CAS No.	1224464-93-0
Molecular Formula	C6H4ClN5
Molecular Weight	181.58 g/mol
Synonyms	5-(6-Chloropyridin-3-yl)-1H-tetrazole; 2-Chloro-5-(1H-tetrazol-5-yl)pyridine; 6-Chloro-3-(1H-tetrazol-5-yl)pyridine; 2-Chloro-5-tetrazol-5-ylpyridine; 5-(6-Chloro-3-pyridyl)tetrazole; 2-Chloro-5-(2H-tetrazol-5-yl)pyridine; 2-Chloro-5-(tetrazol-5-yl)pyridine; 6-Chloro-3-pyridyltetrazole
EINECS	Contact for details

Quality Control

Our 2-Chloro-5-(2H-Tetrazol-5-Yl)Pyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by NMR and IR spectroscopy, to ensure it meets the high standards required for pharmaceutical R&D. Certificates of Analysis (COA) with full traceability are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.