Description

2-(Chloromethyl)-3,5-Difluoropyridine is a versatile and high-value halogenated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its molecular structure, featuring both a reactive chloromethyl group and fluorine substituents, makes it an indispensable intermediate for constructing complex molecules with tailored properties. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical industries for developing new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and anti-infective drugs.
• Agrochemical Synthesis: Used to construct advanced pyridine-based herbicides, fungicides, and insecticides with improved efficacy and selectivity.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in catalysis and material science.
• Fluorinated Compound Research: Essential for introducing fluorine atoms into target molecules to modulate their bioavailability, metabolic stability, and lipophilicity.
• Fine Chemical Production: Employed in the multi-step synthesis of complex dyes, electronic chemicals, and other specialty materials.

Basic Information

Product Name	2-(Chloromethyl)-3,5-Difluoropyridine
CAS No.	1222633-85-3
Molecular Formula	C6H4ClF2N
Molecular Weight	163.55 g/mol
Synonyms	3,5-Difluoro-2-(chloromethyl)pyridine; 2-Chloromethyl-3,5-difluoropyridine; (3,5-Difluoropyridin-2-yl)methyl chloride; 3,5-Difluoro-2-pyridinemethyl chloride
EINECS	Contact for details

Quality Control

Every batch of 2-(Chloromethyl)-3,5-Difluoropyridine is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.