Description

1-(5-Methyl-1H-Pyrrolo[2,3-B]Pyridin-3-Yl)Ethanone is a high-purity, advanced pharmaceutical intermediate belonging to the azaindole class of heterocyclic compounds. This compound is of significant commercial importance due to its role as a critical building block in the synthesis of novel, small-molecule therapeutics. It is primarily sought after by research institutions and pharmaceutical companies engaged in the development of kinase inhibitors and other targeted oncology treatments, where precise molecular structure is paramount for biological activity.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the research and development of protein kinase inhibitors for cancer therapy.
• Oncology Drug Discovery: Used as a core scaffold in medicinal chemistry programs targeting various oncogenic pathways.
• Biochemical Research: Serves as a reference standard or a reagent in biochemical assays and pharmacological studies.
• Organic Synthesis: Employed in advanced organic synthesis to construct complex nitrogen-containing heterocycles for various applications.
• Contract Manufacturing (CMO): Supplied to contract manufacturing organizations for the scale-up and production of active pharmaceutical ingredients (APIs).
• Academic Research: Utilized in university and institutional labs for exploring new chemical entities and reaction methodologies.

Basic Information

Product Name	1-(5-Methyl-1H-Pyrrolo[2,3-B]Pyridin-3-Yl)Ethanone
CAS No.	1222533-85-8
Molecular Formula	C10H10N2O
Molecular Weight	174.20 g/mol
Synonyms	1-(5-Methyl-1H-pyrrolo[2,3-b]pyridin-3-yl)ethan-1-one; 3-Acetyl-5-methyl-1H-pyrrolo[2,3-b]pyridine; 5-Methyl-3-acetyl-1H-pyrrolo[2,3-b]pyridine; 1-(5-Methyl-1H-7-azaindol-3-yl)ethanone; 3-Acetyl-5-methyl-7-azaindole; 1-(5-Methyl-1H-pyrrolo[2,3-b]pyridin-3-yl)ethanone; Azaindole ketone derivative
EINECS	Contact for details

Quality Control

Our production of 1-(5-Methyl-1H-Pyrrolo[2,3-B]Pyridin-3-Yl)Ethanone adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity, essential for sensitive pharmaceutical R&D. All material is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We support compliance with cGMP and ISO 9001 standards where required, and specifications can be aligned with client-specific pharmacopeial needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This compound may be light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.