Description

Evogliptin Tartrate is a high-purity, non-racemic salt form of the potent and selective dipeptidyl peptidase-4 (DPP-4) inhibitor. This compound is of significant value in pharmaceutical research and development, specifically for the treatment of type 2 diabetes mellitus. It is primarily required by pharmaceutical manufacturers, advanced research institutions, and contract development and manufacturing organizations (CDMOs) engaged in the synthesis of novel antidiabetic therapeutics. Evogliptin Tartrate CAS NO 1222102-51-3 represents a critical advanced intermediate for producing high-efficacy, low-side-effect drug formulations.

Application

• Active Pharmaceutical Ingredient (API) Synthesis: Serves as a key chiral intermediate in the commercial-scale production of Evogliptin API.
• Pharmaceutical R&D: Used in preclinical and clinical studies to develop new dosage forms and combination therapies for diabetes.
• Reference Standard: Employed as a high-purity analytical standard for quality control and method validation in pharmaceutical laboratories.
• Process Chemistry: Utilized in optimizing and scaling up synthetic routes for DPP-4 inhibitor类药物.
• Academic Research: Facilitates biochemical and pharmacological studies on DPP-4 enzyme inhibition mechanisms.

Basic Information

Product Name	Evogliptin Tartrate
CAS No.	1222102-51-3
Molecular Formula	C₂₃H₃₀N₄O₇ • C₄H₆O₆ (or contact for full salt formula)
Molecular Weight	Contact for details
Synonyms	(2R)-1-({(3R)-3-Amino-4-(2,4,5-trifluorophenyl)butanoyl}pyrrolidin-2-yl)phosphonic acid tartrate salt; DA-1229 Tartrate; Evogliptin L-Tartrate; (R)-Omarigliptin Tartrate; (R)-MK-3102 Tartrate; DPP-4 Inhibitor DA-1229 Tartrate Salt
EINECS	Contact for details

Quality Control

Our Evogliptin Tartrate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure it meets high-purity standards suitable for pharmaceutical applications. Certificates of Analysis (COA) documenting identity, purity, chiral purity, and impurity profiles are provided and can be tailored to meet specific pharmacopeial or client requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/IR)	Conforms to reference standard
Assay (HPLC)	≥98.0%
Chiral Purity (Chiral HPLC)	≥99.0%
Related Substances (HPLC)	Individual impurity: ≤0.5%; Total impurities: ≤1.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Water Content (KF)	≤1.0%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.