Description

6-(Methylsulfonyl)Nicotinaldehyde is a high-purity, versatile pyridine derivative featuring a reactive aldehyde group and a methylsulfonyl substituent. This compound serves as a critical advanced pharmaceutical intermediate (API) and a valuable building block in modern synthetic chemistry. It is primarily utilized by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and material science sectors for the development of novel active compounds.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of kinase inhibitors and other small-molecule drug candidates targeting various therapeutic areas.
• Agrochemical Synthesis: Building block for creating novel pesticides and herbicides with enhanced efficacy and selectivity.
• Ligand and Catalyst Development: Used in the preparation of specialized ligands for metal-catalyzed cross-coupling reactions.
• Material Science Research: Serves as a monomer or functionalization agent in the development of advanced polymers and functional materials.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological pathways and target engagement.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs for use in bespoke synthesis projects and scale-up processes.

Basic Information

Product Name	6-(Methylsulfonyl)Nicotinaldehyde
CAS No.	1221792-08-0
Molecular Formula	C7H7NO3S
Molecular Weight	185.20 g/mol
Synonyms	6-(Methylsulfonyl)pyridine-3-carboxaldehyde; 3-Formyl-6-(methylsulfonyl)pyridine; 6-Methanesulfonylnicotinaldehyde; 6-Methylsulfonylnicotinaldehyde; 6-(Methylsulfonyl)-3-pyridinecarboxaldehyde; Pyridine-3-carboxaldehyde, 6-(methylsulfonyl)-; 6-Mesylnicotinaldehyde; 6-(Methylsulphonyl)nicotinaldehyde
EINECS	Contact for details

Quality Control

Our 6-(Methylsulfonyl)Nicotinaldehyde is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with customer specifications and industry best practices for high-value intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This material is easily oxidized; for long-term storage, consider keeping under an inert atmosphere such as nitrogen or argon. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.