Description

Imidazo[1,2-A]Pyridine-6-Carbonitrile, 8-Chloro- CAS NO 1221792-07-9 is a high-value, heterocyclic organic compound featuring a fused imidazole and pyridine ring system, functionalized with a nitrile and a chloro substituent. This specific molecular architecture makes it a critical advanced pharmaceutical intermediate (API) and a versatile building block for medicinal chemistry research and development. It is primarily sought after by R&D teams and process chemists in the pharmaceutical, agrochemical, and specialty chemical industries for the synthesis of novel active compounds.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly in therapeutic areas targeting the central nervous system, oncology, and infectious diseases.
• Medicinal Chemistry Building Block: Used extensively in hit-to-lead and lead optimization campaigns to explore structure-activity relationships (SAR) due to its privileged scaffold.
• Agrochemical Research: Serves as a core structure for developing new active ingredients for crop protection products, such as fungicides or insecticides.
• Chemical Biology Probe Synthesis: Utilized to create molecular tools for studying biological pathways and target validation.
• Material Science Research: Investigated as a precursor for organic electronic materials or metal-organic frameworks (MOFs) due to its conjugated system and coordination sites.

Basic Information

Product Name	Imidazo[1,2-A]Pyridine-6-Carbonitrile, 8-Chloro-
CAS No.	1221792-07-9
Molecular Formula	C8H4ClN3
Molecular Weight	177.59 g/mol
Synonyms	8-Chloroimidazo[1,2-a]pyridine-6-carbonitrile; 8-Chloro-6-cyanoimidazo[1,2-a]pyridine; Imidazo[1,2-a]pyridine-6-carbonitrile, 8-chloro-; 1221792-07-9; 8-Chloroimidazo(1,2-a)pyridine-6-carbonitrile; 8-Chloro-6-imidazo[1,2-a]pyridinecarbonitrile
EINECS	Contact for details

Quality Control

Our Imidazo[1,2-A]Pyridine-6-Carbonitrile, 8-Chloro- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and batch-to-batch consistency, meeting the stringent requirements for research and development use. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (HPLC/IR)	Conforms to reference standard
Purity (HPLC)	≥ 97.0% (Typical: 98.0% - 99.5%)
Water Content (KF)	≤ 0.5% w/w
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.