Description

tert-Butyl 4-(3-Oxopropyl)piperazine-1-carboxylate is a high-value, protected piperazine derivative featuring a reactive oxopropyl side chain. This compound serves as a versatile and critical building block in modern organic synthesis, enabling the efficient construction of complex molecular architectures. It is primarily utilized by pharmaceutical and agrochemical research organizations for the development of new active ingredients, including kinase inhibitors and other small molecule therapeutics.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of biologically active molecules, particularly kinase inhibitors and other targeted therapies.
• Agrochemical Research: Used in the development of novel crop protection agents and herbicides.
• Chemical Synthesis Building Block: The reactive ketone and protected amine functionalities allow for diverse chemical modifications, including reductive amination, Grignard additions, and nucleophilic substitutions.
• Ligand and Catalyst Development: Employed in the creation of novel chelating ligands and organocatalysts for asymmetric synthesis.
• Peptidomimetic Chemistry: The piperazine core is a common scaffold in peptidomimetics, used to modulate the pharmacokinetic properties of drug candidates.
• Material Science Research: Potential monomer or cross-linker in the synthesis of specialized polymers and functional materials.

Basic Information

Item	Details
Product Name	tert-Butyl 4-(3-Oxopropyl)piperazine-1-carboxylate
CAS No.	1221492-48-3
Molecular Formula	C12H22N2O3
Molecular Weight	242.32 g/mol
Synonyms	1-Boc-4-(3-oxopropyl)piperazine; tert-Butyl 4-(3-oxopropyl)-1-piperazinecarboxylate; 1-(tert-Butoxycarbonyl)-4-(3-oxopropyl)piperazine; 4-(3-Oxopropyl)piperazine-1-carboxylic acid tert-butyl ester; 3-(4-(tert-Butoxycarbonyl)piperazin-1-yl)propanal; Boc-4-(3-oxopropyl)piperazine; 1-Boc-4-(3-oxo-propyl)-piperazine
EINECS	Contact for details

Quality Control

Our tert-Butyl 4-(3-Oxopropyl)piperazine-1-carboxylate is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with customer specifications and industry standards for research-grade chemicals.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.