Description

2-Bromo-6-(Trifluoromethoxy)Pyridine is a high-value, multi-functional halogenated pyridine derivative. This compound serves as a critical advanced pharmaceutical intermediate and versatile organic synthesis building block, enabling the construction of complex molecular architectures. It is primarily utilized by R&D and production teams in the pharmaceutical, agrochemical, and material science industries for developing novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Synthesis: Building block for developing new generation herbicides, fungicides, and insecticides with enhanced efficacy and environmental profiles.
• Ligand and Catalyst Development: Used to create novel pyridine-based ligands for transition metal catalysis in fine chemical manufacturing.
• Material Science Research: Intermediate for synthesizing organic electronic materials, such as charge-transport layers or components for OLEDs.
• Cross-Coupling Reactions: Serves as a substrate in Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to form biaryl structures.
• Functional Group Transformation: The bromine moiety allows for further functionalization via nucleophilic substitution or metal-halogen exchange reactions.

Basic Information

Product Name	2-Bromo-6-(Trifluoromethoxy)Pyridine
CAS No.	1221172-10-6
Molecular Formula	C6H3BrF3NO
Molecular Weight	241.99 g/mol
Synonyms	2-Bromo-6-(trifluoromethoxy)pyridine; 6-Bromo-2-(trifluoromethoxy)pyridine; Pyridine, 2-bromo-6-(trifluoromethoxy)-; 2-Bromo-6-trifluoromethoxypyridine; 1221172-10-6; 2-Br-6-OCF3-Pyridine
EINECS	Contact for details

Quality Control

Our 2-Bromo-6-(Trifluoromethoxy)Pyridine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with customer specifications. Our quality commitment supports applications requiring high-purity intermediates for regulatory filings.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly closed and stored in a dry environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.