Description

2-Chloro-6-(Trifluoromethoxy)Pyridin-3-Amine is a high-value, halogenated pyridine derivative serving as a critical building block in advanced organic synthesis. Its unique structure, featuring both chloro and trifluoromethoxy substituents, makes it an essential intermediate for creating complex molecules with tailored properties. This compound is primarily sought after by R&D and process development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, where the trifluoromethoxy group can enhance biological activity and environmental stability.
• Material Science Research: Serves as a monomer or functionalization agent in the creation of specialty polymers and advanced organic electronic materials.
• Ligand and Catalyst Development: Employed in the design of novel nitrogen-containing ligands for transition metal catalysis and organocatalysts.
• Chemical Biology Probes: Utilized as a scaffold for developing molecular probes and diagnostic agents due to its derivatizable amine group.

Basic Information

Product Name	2-Chloro-6-(Trifluoromethoxy)Pyridin-3-Amine
CAS No.	1221172-05-9
Molecular Formula	C6H4ClF3N2O
Molecular Weight	212.56 g/mol
Synonyms	3-Amino-2-chloro-6-(trifluoromethoxy)pyridine; 2-Chloro-6-(trifluoromethoxy)-3-pyridinamine; 2-Chloro-6-(trifluoromethoxy)pyridin-3-ylamine; 2-Chloro-6-trifluoromethoxypyridin-3-amine; 1221172-05-9; 3-Pyridinamine, 2-chloro-6-(trifluoromethoxy)-
EINECS	Contact for details

Quality Control

Every batch of 2-Chloro-6-(Trifluoromethoxy)Pyridin-3-Amine is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for research and scale-up applications. A detailed Certificate of Analysis (COA) including purity (HPLC), identity confirmation (NMR, IR), and impurity profile is supplied with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider inert atmosphere conditions to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.