Description

2-Chloro-4-Iodo-6-(Trifluoromethoxy)Pyridine is a high-value, multi-halogenated pyridine derivative, distinguished by its unique trifluoromethoxy substituent. This compound is a critical advanced pharmaceutical intermediate (API) and a versatile building block in modern synthetic chemistry, prized for its ability to impart desirable physicochemical properties to target molecules. It is primarily sought after by R&D and production teams in the pharmaceutical and agrochemical sectors for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of complex drug candidates, particularly in medicinal chemistry programs targeting central nervous system (CNS) disorders and anti-infective agents.
• Agrochemical Synthesis: Serves as a crucial precursor for developing next-generation herbicides, fungicides, and insecticides, where the halogen and trifluoromethoxy groups enhance biological activity and environmental stability.
• Ligand & Catalyst Development: Used in organometallic chemistry to create novel ligands for transition metal catalysts, enabling more efficient cross-coupling and other catalytic transformations.
• Material Science Research: Employed in the synthesis of functionalized polymers and organic electronic materials, where its structure can tune electronic properties.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring specific halogenated pyridine scaffolds.

Basic Information

Product Name	2-Chloro-4-Iodo-6-(Trifluoromethoxy)Pyridine
CAS No.	1221171-96-5
Molecular Formula	C6H2ClF3INO
Molecular Weight	323.44 g/mol
Synonyms	2-Chloro-4-iodo-6-(trifluoromethoxy)pyridine; 6-(Trifluoromethoxy)-2-chloro-4-iodopyridine; 4-Iodo-2-chloro-6-(trifluoromethoxy)pyridine; 2-Chloro-4-iodo-6-trifluoromethoxypyridine; Pyridine, 2-chloro-4-iodo-6-(trifluoromethoxy)-; CAS 1221171-96-5
EINECS	Contact for details

Quality Control

Every batch of 2-Chloro-4-Iodo-6-(Trifluoromethoxy)Pyridine is manufactured and tested under a strict ISO 9001:2015 quality management system. Our products undergo rigorous quality testing, including advanced chromatographic and spectroscopic methods, to ensure high purity and batch-to-batch consistency suitable for research and commercial-scale synthesis. Comprehensive Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong bases and reducing agents. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single unknown impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.