Description

2-Chloro-4-Iodo-5-(Trifluoromethoxy)Pyridine is a high-value, multi-halogenated pyridine derivative that serves as a critical building block in advanced organic synthesis. Its unique structure, featuring chlorine, iodine, and trifluoromethoxy substituents, makes it an indispensable intermediate for creating complex molecules with tailored electronic and steric properties. This compound is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the construction of novel drug candidates, particularly in medicinal chemistry programs targeting central nervous system (CNS) disorders, anti-infectives, and oncology.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides, fungicides, and insecticides, where the halogenated pyridine core contributes to biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a precursor for sophisticated ligands in transition metal catalysis, enabling challenging cross-coupling and other transformative reactions.
• Material Science Research: Employed in the synthesis of organic electronic materials, such as semiconductors and liquid crystals, where its halogen atoms allow for further functionalization and tuning of material properties.
• Custom Synthesis and Contract Manufacturing: A vital starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the fine chemical and life science sectors.

Basic Information

Product Name	2-Chloro-4-Iodo-5-(Trifluoromethoxy)Pyridine
CAS No.	1221171-84-1
Molecular Formula	C6H2ClF3INO
Molecular Weight	337.44 g/mol
Synonyms	2-Chloro-4-iodo-5-(trifluoromethoxy)pyridine; 5-(Trifluoromethoxy)-2-chloro-4-iodopyridine; Pyridine, 2-chloro-4-iodo-5-(trifluoromethoxy)-; 2-Chloro-4-iodo-5-(trifluoromethoxyl)pyridine
EINECS	Contact for details

Quality Control

We supply 2-Chloro-4-Iodo-5-(Trifluoromethoxy)Pyridine in high-purity grades suitable for research and development. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request. We adhere to strict quality management protocols to ensure batch-to-batch consistency and reliability for your critical synthetic applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong acids and incompatible materials. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.