Description

2-Chloro-3-(trifluoromethoxy)pyridin-4-amine is a high-value, multi-functional pyridine derivative that serves as a critical building block in advanced chemical synthesis. Its unique structure, featuring both chloro and trifluoromethoxy substituents, makes it an essential intermediate for creating complex molecules with tailored properties. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of new drug candidates targeting central nervous system and metabolic diseases.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides, herbicides, and fungicides, where the trifluoromethoxy group can enhance biological activity and environmental stability.
• Material Science Research: Serves as a precursor for the development of specialty chemicals, liquid crystals, and advanced polymers requiring specific electronic or steric properties.
• Chemical Synthesis: A versatile reagent for introducing the 2-chloro-3-(trifluoromethoxy)pyridin-4-yl moiety into more complex molecular architectures in medicinal and process chemistry.

Basic Information

Product Name	2-Chloro-3-(trifluoromethoxy)pyridin-4-amine
CAS No.	1221171-79-4
Molecular Formula	C6H4ClF3N2O
Molecular Weight	212.56 g/mol
Synonyms	4-Amino-2-chloro-3-(trifluoromethoxy)pyridine; 2-Chloro-3-(trifluoromethoxy)-4-pyridinamine; 4-Pyridinamine, 2-chloro-3-(trifluoromethoxy)-; 2-Chloro-3-trifluoromethoxypyridin-4-ylamine; 1221171-79-4; 2-Chloro-3-(trifluoromethoxy)-4-aminopyridine
EINECS	Contact for details

Quality Control

Our 2-Chloro-3-(trifluoromethoxy)pyridin-4-amine is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and development applications. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, identity, and impurity profiles. Our quality management system is designed to meet the stringent requirements of our global customer base in advanced chemical synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Single Maximum Impurity (HPLC)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.