Description

1-(5-Chloro-1-Isopropyl-1H-Pyrrolo[2,3-C]Pyridin-3-Yl)Ethanone is a high-purity, advanced pharmaceutical intermediate characterized by its unique pyrrolopyridine core structure. This compound is of significant commercial value for its role as a critical building block in the synthesis of novel, biologically active molecules. It is primarily sought after by research institutions and pharmaceutical manufacturers engaged in the development of new therapeutic agents, particularly within oncology and central nervous system (CNS) drug discovery pipelines.

Application

• Pharmaceutical Intermediate: Serves as a key synthetic precursor in the research and development of new active pharmaceutical ingredients (APIs).
• Kinase Inhibitor Synthesis: Used in the construction of complex heterocyclic scaffolds targeting various kinase enzymes for potential cancer therapies.
• Medicinal Chemistry Research: A valuable building block for constructing compound libraries for high-throughput screening (HTS) and structure-activity relationship (SAR) studies.
• Biochemical Tool Compound: May be utilized in biochemical assays to study specific biological pathways and target interactions.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects under cGMP conditions.
• Academic Research: Employed in university and institutional labs for exploratory synthetic chemistry and drug discovery projects.

Basic Information

Product Name	1-(5-Chloro-1-Isopropyl-1H-Pyrrolo[2,3-C]Pyridin-3-Yl)Ethanone
CAS No.	1221153-80-5
Molecular Formula	C12H13ClN2O
Molecular Weight	236.70 g/mol
Synonyms	5-Chloro-1-isopropyl-3-acetyl-1H-pyrrolo[2,3-c]pyridine; 1-(5-Chloro-1-propan-2-ylpyrrolo[2,3-c]pyridin-3-yl)ethanone; 3-Acetyl-5-chloro-1-isopropyl-1H-pyrrolo[2,3-c]pyridine; Ethanone, 1-(5-chloro-1-(1-methylethyl)-1H-pyrrolo[2,3-c]pyridin-3-yl)-; CAS 1221153-80-5
EINECS	Contact for details

Quality Control

Our 1-(5-Chloro-1-Isopropyl-1H-Pyrrolo[2,3-C]Pyridin-3-Yl)Ethanone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis by GC. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our quality commitment ensures material suitable for demanding research and pre-clinical development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be amber or opaque.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.