Description

5-Chloro-Pyridine-2-Sulfonyl Chloride Hydrochloride is a high-purity, reactive sulfonyl chloride derivative used as a critical building block in advanced organic synthesis. Its dual functionality makes it an essential intermediate for constructing complex molecules with tailored properties. This compound is primarily utilized by research and development chemists in the pharmaceutical and agrochemical industries for creating novel active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of sulfonamide-based drug candidates, including enzyme inhibitors and receptor antagonists.
• Agrochemical Synthesis: Used in the development of new herbicides, fungicides, and insecticides that require the pyridine-sulfonyl chloride scaffold.
• Material Science Research: Serves as a precursor for creating functional polymers and advanced materials with specific surface properties.
• Chemical Biology Probes: Employed in the design and synthesis of activity-based probes for studying enzyme function and protein labeling.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Product Name	5-Chloro-Pyridine-2-Sulfonyl Chloride Hydrochloride
CAS No.	1220039-85-9
Molecular Formula	C5H4Cl2NO2S • HCl
Molecular Weight	274.93 g/mol
Synonyms	2-Pyridinesulfonyl chloride, 5-chloro-, hydrochloride; 5-Chloro-2-pyridinesulfonyl chloride hydrochloride; 5-Chloropyridine-2-sulfonyl chloride hydrochloride; 5-Chloro-2-pyridylsulfonyl chloride hydrochloride; 5-Chloro-2-sulfonylchloridopyridine hydrochloride; 1220039-85-9; 5-Cl-Py-2-SO2Cl • HCl
EINECS	Contact for details

Quality Control

Our 5-Chloro-Pyridine-2-Sulfonyl Chloride Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and Karl Fischer titration for moisture content, to ensure it meets the stringent requirements for research and process chemistry. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere after opening. Keep away from strong acids and incompatible organic solvents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.