Description

4-[3-Amino-4-(Methylsulfonyl)Phenyl]-2-Piperazinone is a high-purity, advanced pharmaceutical intermediate characterized by its unique piperazinone core and functionalized phenyl ring. This compound is critical for the synthesis of novel active pharmaceutical ingredients (APIs) targeting complex therapeutic pathways. It is primarily required by research institutions and pharmaceutical manufacturers engaged in the development of new drug candidates, particularly in the areas of central nervous system (CNS) and oncology research.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of novel drug candidates, particularly for CNS and oncology targets.
• Chemical Research & Development: Used as a versatile scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization.
• API Synthesis: Integral in multi-step synthetic routes for producing complex, high-value active pharmaceutical ingredients.
• Contract Manufacturing (CMO): Supplied to contract research and manufacturing organizations for custom synthesis projects.
• Academic Research: Utilized in university and institutional labs for investigating new heterocyclic chemistry and pharmacological mechanisms.

Basic Information

Product Name	4-[3-Amino-4-(Methylsulfonyl)Phenyl]-2-Piperazinone
CAS No.	1220039-18-8
Molecular Formula	C11H15N3O3S
Molecular Weight	269.32 g/mol
Synonyms	2-Piperazinone, 4-[3-amino-4-(methylsulfonyl)phenyl]-; 4-(3-Amino-4-methanesulfonylphenyl)piperazin-2-one; 4-(3-Amino-4-(methylsulfonyl)phenyl)-2-piperazinone; 4-(3-Amino-4-mesylphenyl)piperazin-2-one; CAS 1220039-18-8; 4-[3-Amino-4-(Methylsulfonyl)Phenyl]-2-Piperazinone; 4-(3-Amino-4-(methylsulfonyl)phenyl)piperazin-2-one
EINECS	Contact for details

Quality Control

Our 4-[3-Amino-4-(Methylsulfonyl)Phenyl]-2-Piperazinone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (typically 15-25°C). The product may be hygroscopic; keep the container tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.