Description

4-(3-Piperidinyl)-2-Piperazinone Dihydrochloride is a high-purity, specialized organic salt used as a critical building block in advanced chemical synthesis. This compound matters for its role as a key intermediate in the development of novel pharmaceutical candidates, particularly in central nervous system (CNS) and other therapeutic areas. It is primarily needed by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers engaged in medicinal chemistry and process development.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug molecules targeting neurological receptors.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new therapeutic agents.
• Process Chemistry Development: Serves as a starting material for scaling up synthetic routes under Good Manufacturing Practice (GMP) conditions.
• Biochemical Research: Potential use as a ligand or probe in biochemical assays and pharmacological studies.
• Custom Synthesis: Employed by contract research and manufacturing organizations (CRMOs) for bespoke chemical synthesis projects.
• Reference Standard: Can be supplied as a high-purity standard for analytical method development and quality control.

Basic Information

Product Name	4-(3-Piperidinyl)-2-Piperazinone Dihydrochloride
CAS No.	1220037-88-6
Molecular Formula	C9H17N3O · 2HCl
Molecular Weight	280.18 g/mol
Synonyms	2-Piperazinone, 4-(3-piperidinyl)-, dihydrochloride; 4-(Piperidin-3-yl)piperazin-2-one dihydrochloride; 3-(2-Oxopiperazin-4-yl)piperidine dihydrochloride; 4-(3-Piperidyl)-2-piperazinone dihydrochloride; 1220037-88-6; UNII-Contact for details; 4-(3-Piperidinyl)-2-piperazinone hydrochloride (1:2)
EINECS	Contact for details

Quality Control

Our 4-(3-Piperidinyl)-2-Piperazinone Dihydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the high standards required for pharmaceutical research. Certificates of Analysis (COA) with detailed specifications are provided and can be tailored to meet specific project or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.