Description

2-Chloro-4-Methylphenyl 3-Piperidinylmethyl Etherhydrochloride is a high-purity organic salt compound, primarily utilized as a key pharmaceutical intermediate. Its value lies in its role as a sophisticated building block for the synthesis of complex active pharmaceutical ingredients (APIs) and other fine chemicals. This product is essential for research and development laboratories, process chemists, and manufacturers in the pharmaceutical and agrochemical industries who require reliable, high-quality intermediates for their synthesis workflows.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of novel drug candidates, particularly in central nervous system (CNS) and other therapeutic areas.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, leveraging its specific chlorinated aromatic and piperidine motifs.
• Chemical Research & Development: Serves as a versatile scaffold for medicinal chemistry, enabling the exploration of new chemical entities and structure-activity relationships (SAR).
• Process Chemistry & Scale-up: Employed in the optimization and pilot-scale production of target molecules, requiring consistent quality and supply.
• Reference Standard: Can be supplied as a high-purity standard for analytical method development, quality control, and regulatory submissions.

Basic Information

Product Name	2-Chloro-4-Methylphenyl 3-Piperidinylmethyl Etherhydrochloride
CAS No.	1220027-72-4
Molecular Formula	C14H21Cl2NO
Molecular Weight	290.23 g/mol
Synonyms	1-(3-((2-Chloro-4-methylphenoxy)methyl)piperidin-1-yl)ethanone Hydrochloride (common IUPAC-style); 2-Chloro-4-methylphenyl 3-piperidinylmethyl ether hydrochloride; 3-((2-Chloro-p-tolyloxy)methyl)piperidine hydrochloride; Piperidine, 3-[(2-chloro-4-methylphenoxy)methyl]-, hydrochloride (1:1); CAS 1220027-72-4
EINECS	Contact for details

Quality Control

Our 2-Chloro-4-Methylphenyl 3-Piperidinylmethyl Etherhydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the high standards required for pharmaceutical intermediate applications. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed to prevent absorption of atmospheric moisture, which can affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.