Description

2-[4-(2-Pyrrolidinylmethyl)-1-Piperazinyl]-1-Ethanol Dihydrochloride is a high-purity, specialized organic salt used as a critical intermediate in advanced chemical synthesis. Its value lies in providing a reliable and consistent building block for the development of novel pharmaceutical compounds and research chemicals. This product is essential for R&D chemists and process development scientists in the pharmaceutical, biotechnology, and fine chemical industries who require precise molecular scaffolds for drug discovery and development programs.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of active pharmaceutical ingredients (APIs) and novel drug candidates, particularly in central nervous system (CNS) research.
• Chemical Synthesis Building Block: Used in medicinal chemistry for constructing complex molecules with piperazine and pyrrolidine motifs, which are common pharmacophores.
• Biochemical Research: Employed in academic and industrial research laboratories for studying receptor-ligand interactions and developing new therapeutic agents.
• Process Chemistry: Utilized in scale-up and optimization studies for the commercial production of specialized fine chemicals.
• Reference Standard: Can be supplied as a high-purity standard for analytical method development and quality control in manufacturing.

Basic Information

Product Name	2-[4-(2-Pyrrolidinylmethyl)-1-Piperazinyl]-1-Ethanol Dihydrochloride
CAS No.	1220027-37-1
Molecular Formula	C11H23N3O · 2HCl
Molecular Weight	310.25 g/mol (as free base: 213.32 g/mol)
Synonyms	1-(2-Hydroxyethyl)-4-[(pyrrolidin-2-yl)methyl]piperazine dihydrochloride; 2-{4-[(2-Pyrrolidinyl)methyl]-1-piperazinyl}ethanol dihydrochloride; 2-(4-((Pyrrolidin-2-yl)methyl)piperazin-1-yl)ethanol dihydrochloride; 1-(2-Hydroxyethyl)-4-(pyrrolidin-2-ylmethyl)piperazine dihydrochloride; UNII-2H6V2Q8W0F (component); 2-Pyrrolidinylmethyl piperazine ethanol dihydrochloride
EINECS	Contact for details

Quality Control

Our 2-[4-(2-Pyrrolidinylmethyl)-1-Piperazinyl]-1-Ethanol Dihydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and synthesis. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to maintain stability and purity. For long-term storage, consider desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Maximum Impurity	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.