Description

2-Bromo-6-(3-Pyrrolidinylmethoxy)Pyridinehydrochloride is a high-purity organic building block and pharmaceutical intermediate of significant commercial interest. This compound matters for its role in the synthesis of complex molecules, particularly in medicinal chemistry research and development. Pharmaceutical companies, contract research organizations (CROs), and fine chemical manufacturers need it for creating novel drug candidates targeting neurological and other therapeutic areas.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs) for central nervous system (CNS) drugs.
• Medicinal Chemistry Research: Used in hit-to-lead and lead optimization stages for creating libraries of novel bioactive compounds.
• Ligand Synthesis: Serves as a precursor for the development of receptor ligands and enzyme inhibitors in biochemical assays.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying biological pathways and protein function.
• Custom Synthesis: A starting material for contract manufacturing organizations (CMOs) producing specialized fine chemicals on demand.
• Academic Research: Utilized in university and institutional labs for exploratory synthetic chemistry and drug discovery projects.

Basic Information

Product Name	2-Bromo-6-(3-Pyrrolidinylmethoxy)Pyridinehydrochloride
CAS No.	1220020-45-0
Molecular Formula	C10H14BrN2O·HCl
Molecular Weight	307.60 g/mol (Free base: 270.14 g/mol)
Synonyms	2-Bromo-6-[(3-pyrrolidinyl)methoxy]pyridine hydrochloride; 6-Bromo-2-[(3-pyrrolidinyl)methoxy]pyridine HCl; 2-Bromo-6-(pyrrolidin-3-ylmethoxy)pyridine hydrochloride; 2-Bromo-6-(3-pyrrolidinylmethoxy)pyridine HCl; Pyrrolidine, 3-[(6-bromo-2-pyridinyloxy)methyl]-, hydrochloride (1:1); (3-((6-Bromopyridin-2-yloxy)methyl)pyrrolidin-1-ium) chloride
EINECS	Contact for details

Quality Control

Our 2-Bromo-6-(3-Pyrrolidinylmethoxy)Pyridinehydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by NMR and mass spectrometry, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which can affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥97.0%
Assay (Titration)	≥98.0% (on anhydrous basis)
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.