Description

n-Isonicotinoyl-2-Methylalanine is a specialized organic compound featuring a nicotinoyl moiety linked to a modified alanine backbone. This structure makes it a valuable building block (synthon) and key intermediate in advanced organic synthesis, particularly for the development of novel pharmaceutical agents and bioactive molecules. It is primarily utilized by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers engaged in medicinal chemistry and process development.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of potential drug candidates, especially those targeting neurological or metabolic pathways.
• Medicinal Chemistry Research: Used as a scaffold or building block for constructing compound libraries in high-throughput screening and structure-activity relationship (SAR) studies.
• Peptidomimetic Development: Its structure, containing both amide and carboxylic acid functionalities, makes it suitable for designing peptide analogs and mimetics.
• Bioconjugation & Probe Synthesis: Can be utilized for labeling biomolecules or creating chemical probes for biochemical and diagnostic applications.
• Academic & Industrial R&D: Employed in synthetic organic chemistry research for methodological development and exploring new chemical spaces.

Basic Information

Product Name	n-Isonicotinoyl-2-Methylalanine
CAS No.	1219979-67-5
Molecular Formula	C11H12N2O3
Molecular Weight	220.23 g/mol
Synonyms	2-Methyl-2-[(pyridine-4-carbonyl)amino]propanoic acid; (2-Methyl-2-{[(pyridin-4-yl)carbonyl]amino}propanoic acid); N-Isonicotinoyl-2-methylalanine; 2-Methylalanine N-isonicotinoyl derivative; 4-Pyridinecarboxamide, N-(1-carboxy-1-methylethyl)-; Isonicotinic acid, 2-methylalaninamide; Alanine, N-isonicotinoyl-2-methyl-
EINECS	Contact for details

Quality Control

Our n-Isonicotinoyl-2-Methylalanine is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by spectroscopic methods (NMR, IR, MS), to ensure it meets the high standards required for research and development applications. A Certificate of Analysis (COA) detailing batch-specific results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using a desiccator.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.