Description

2-[Ethyl(4-Piperidinyl)Amino]-1-Ethanoldihydrochloride is a high-purity organic salt with significant utility in advanced chemical synthesis. This compound serves as a critical building block and intermediate in the development of complex pharmaceutical molecules, particularly those targeting neurological and receptor-based pathways. It is essential for research institutions, contract development and manufacturing organizations (CDMOs), and pharmaceutical companies engaged in the synthesis of novel active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of novel drug candidates, especially within central nervous system (CNS) and receptor modulator research.
• Chemical Research & Development: Used as a versatile synthon in medicinal chemistry for constructing complex nitrogen-containing heterocycles and amine derivatives.
• Active Pharmaceutical Ingredient (API) Synthesis: Employed in the production route of specific APIs where its piperidinyl-ethanolamine structure is integral to the final molecule's activity.
• Process Chemistry & Scale-Up: Serves as a validated intermediate for process optimization and pilot-scale manufacturing under GMP conditions for clinical trial material.
• Biochemical Research: Utilized in the study of enzyme inhibitors and receptor ligands due to its specific amine functionality.
• Custom Synthesis Projects: A starting material for contract research organizations (CROs) and specialty chemical suppliers fulfilling bespoke synthesis requests.

Basic Information

Product Name	2-[Ethyl(4-Piperidinyl)Amino]-1-Ethanoldihydrochloride
CAS No.	1219979-66-4
Molecular Formula	C9H21N2O · 2HCl
Molecular Weight	257.20 g/mol (as dihydrochloride salt)
Synonyms	2-[Ethyl(4-piperidyl)amino]ethanol dihydrochloride; 2-(Ethyl(piperidin-4-yl)amino)ethan-1-ol dihydrochloride; N-Ethyl-N-(4-piperidinyl)ethanolamine dihydrochloride; 4-[Ethyl(2-hydroxyethyl)amino]piperidine dihydrochloride; 2-(Ethyl(4-piperidinyl)amino)ethanol dihydrochloride; Ethanol, 2-[ethyl(4-piperidinyl)amino]-, dihydrochloride
EINECS	Contact for details

Quality Control

Our 2-[Ethyl(4-Piperidinyl)Amino]-1-Ethanoldihydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, identity confirmation via IR and NMR spectroscopy, and stringent control of residual solvents and impurities. Certificates of Analysis (COA) documenting full compliance with agreed specifications are provided with every shipment. We support development and commercial projects requiring ICH stability data and regulatory starting material documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which can affect stability and handling properties. For long-term storage, consider desiccants or inert atmosphere packaging.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Heavy Metals	< 20 ppm
Related Substances (HPLC)	Total impurities < 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.