Description

2-(4-Piperidinyl)Ethyl Isonicotinate Hydrochloride is a high-purity, specialized organic salt used as a critical intermediate in advanced pharmaceutical synthesis. This compound is valued for its role in constructing complex molecular architectures, particularly in the development of active pharmaceutical ingredients (APIs) and novel therapeutic agents. It is primarily required by research institutions, pharmaceutical R&D laboratories, and fine chemical manufacturers engaged in medicinal chemistry and process development.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug molecules, particularly those targeting neurological and metabolic pathways.
• Medicinal Chemistry Research: Used in the discovery and optimization of new chemical entities (NCEs) and lead compounds during preclinical development.
• Process Chemistry Development: Serves as a standard or starting material for scaling up synthetic routes under Good Manufacturing Practice (GMP) conditions.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying enzyme function and receptor interactions.
• Academic Research: Employed in university and institutional labs for synthetic methodology development and structure-activity relationship (SAR) studies.

Basic Information

Product Name	2-(4-Piperidinyl)Ethyl Isonicotinate Hydrochloride
CAS No.	1219979-31-3
Molecular Formula	C13H19ClN2O2
Molecular Weight	270.76 g/mol
Synonyms	4-[2-(Isonicotinoyloxy)ethyl]piperidine hydrochloride; 2-(Piperidin-4-yl)ethyl isonicotinate hydrochloride; 4-(2-Isonicotinoyloxyethyl)piperidine HCl; Isonicotinic acid 2-(4-piperidinyl)ethyl ester hydrochloride; 1,2,3,6-Tetrahydropyridine-4-carboxylic acid 2-(4-piperidinyl)ethyl ester hydrochloride (related); Contact for additional names.
EINECS	Contact for details

Quality Control

Our 2-(4-Piperidinyl)Ethyl Isonicotinate Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and heavy metals to ensure it meets the stringent requirements for pharmaceutical intermediates. A detailed Certificate of Analysis (COA) is provided with every shipment, and custom synthesis to meet specific pharmacopeial or internal specifications is available.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.